Washington University, St. LouisEngineering

Heinz Schaettler

Full Professor
Professor Schaettler has a Ph.D. degree in Mathematics from Rutgers University and, after holding a one year postdoctoral position at the University of California in Davis, joined the faculty of the Department of Systems Science and Mathematics at Washington University in St. Louis in 1987.
Research In Professor Schaettler's research methodologies from dynamical systems theory and optimal control are applied to the analysis of mathematical models motivated by practical problems. In his current research, done jointly with U. Ledzewicz, he is focused on various models that describe selected aspects of cancer treatments such as administration of chemotherapeutic agents in the presence of tumor heterogeneity, angiogenic signaling or tumor immune system interactions. In the past, he has worked on models arising in physics (subatomic cooling), economics (principal-agent problem), power systems (differential-algebraic models for voltage stability problems), electronics (minimization of base transit time in HBT's) and more.
Selected Publications
H. Schättler and U. Ledzewicz, Optimal Control for Mathematical Models of Cancer Therapies – An Application of Geometric Methods, Springer, 2015, to appear
H. Schättler, U. Ledzewicz and H. Maurer, Sufficient conditions for strong local optimality in optimal control problems with L2-type objectives and control constraints, Discrete and Continuous Dynamical Systems, Series B, 19(8), 2014, pp. 2657—2679
H. Schättler and U. Ledzewicz, Geometric Optimal Control - Theory, Methods and Examples, Springer, 2012
D. Stefanatos, H. Schättler and J.S. Li, Minimum-time frictionless atomic cooling in harmonic traps, SIAM J on Control and Optimization, 49(6), 2011, pp. 2440-2462
U. Ledzewicz and Heinz Schättler, Anti-angiogenic therapy in cancer treatment as an optimal control problem, SIAM J. on Control and Optimization, 46 (3), 2007, pp. 1052-1079
V. Venkatasubramanian, H. Schättler, J. Zaborszky: Dynamics of large constrained nonlinear systems - A taxonomy theory, Proceedings of the IEEE, Special Issue on Nonlinear Phenomena in Power Systems, 83 (11), 1995, pp. 1530-1561
Selected Research
Regular synthesis for multi-input optimal control problems with applications to biomedicine, (PI) NSF, DMS- 1311729, 2013-2016
Optimal control of multi-input mathematical models for tumor dynamics under combination therapies, (PI) NSF, DMS-1008209, 2010 - 2013
Analysis of optimal and suboptimal controls for mathematical models arising in novel cancer therapies, (PI) NSF, DMS-0707410, 2007 - 2010
Contact Heinz Schaettler
Address 1 Brookings Drive
Campus Box 1127
City/St/Zip St. Louis, MO 63130

Bryan Hall, Room 229

Phone (314) 935-6019
Fax (314) 935-3248
Email hms@wustl.edu
Other Appt.

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PhD, Rutgers University, 1986
Diplom-Mathematiker, Bayerische Julius-Maximilians Universitaet Wuerzburg, 1982

Washington University in St. Louis School of Engineering & Applied Science, Department of Electrical & Systems Engineering

Green Hall, CB 1042, 1 Brookings Drive, Saint Louis, MO, USA 63130
Phone: (314) 935-5565, Fax: (314) 935-7500

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